Evidence about health-system arrangements
Below we provide the ‘best’ living evidence syntheses currently available (i.e., the highest quality, most regularly updated living evidence syntheses) about health-system arrangements to respond to COVID-19. All other evidence syntheses can be found in the searchable COVID-END inventory of evidence syntheses, which is organized using the COVID-END taxonomy of decisions.
|Topic addressed||Criteria for 'best evidence synthesis'||Details to support relevance assessment||Additional decision-relevant details||Citation|
|Date of last search||Quality (AMSTAR) rating||Evidence-certainty (e.g., GRADE) assessment available||Key findings||Living evidence synthesis||Type of synthesis||Type of question|
|Vaccine roll-out||2021-02-03||5/9||No||Evidence shows that negative beliefs about vaccine efficacy and safety were associated with lower vaccination acceptance among healthcare workers, non-physician health professionals were more likely to have lower acceptance rates, and having a history of accepting influenza vaccination was associated with an increase COVID-19 vaccine acceptance rate [Review of studies of unknown quality conducted during the COVID-19 pandemic and before]||Yes (row content last checked on 2023-09-07)||Rapid review||Other||Crawshaw, J., Konnyu, K., Castillo, G., van Allen, Z., Grimshaw, JM., Presseau, J. Factors affecting healthcare worker COVID-19 vaccination acceptance and uptake: A living behavioural science evidence synthesis (v2, May 18th, 2021). Ottawa: Ottawa Hospital Research Institute, May 18, 2021.|
|2021-04-20||5/9||No||Studies show that vaccination acceptance rates varied in different geographical settings from 40 %to 92%, whereas capability factors, opportunity factors and motivation factors were key important factors driving vaccination acceptance among the general public [Review of studies of unknown quality]||Yes (row content last checked on 2023-09-07)||Rapid review||Other|
Crawshaw, J., Konnyu, K., Castillo, G., van Allen, Z., Grimshaw, JM., Presseau, J. Factors affecting COVID-19 vaccination acceptance and uptake among the general public: A living behavioural science evidence synthesis (v1.0, Apr 30th, 2021). Ottawa: Ottawa Hospital Research Institute,
Apr 30, 2021
|Long-term care home ownership status||2021-01-26||8/10||No||Although evidence shows that for-profit ownership in care homes for older people has not been consistently associated with COVID-19 outbreaks, some studies show that they accounted for a larger proportion of cumulative infections and deaths, which could be explained by less access to personal protection equipment in these facilities [Review of observational studies mainly of low quality]||Yes (row content last checked on 2023-09-07)||Full review||Other||Bach-Mortensen AM, Verboom B, Esposti MD. Ownership and COVID-19 in care homes for older people: A living systematic review of outbreaks, infections, and mortalities. medRxiv. 2021.|
|Care models for post-COVID care||2021-10-07||6/9||No||Twenty international care models have been found to treat long COVID-19 symptoms, with the five most common principles being multidisciplinary teams, integrated care, continuity or coordination of care, self-management and evidence-based care; no evidence on the impact or costs of these models have been found||Yes (row content last checked on 2023-09-07)||Full review||Other||Decary S, Dugas M, Stefan T, Langlois L, Skidmore B, Bhéreur A, and LeBlanc A.|
|Maternal and newborn care||2021-05-14||9/11||No||Compared to pre-pandemic levels, no differences have been found in the adjusted pre-term birth or maternal mortality rates during the COVID-19 pandemic [Review of studies of moderate quality with important heterogeneity among some of the outcomes]||Yes (row content last checked on 2023-09-07)||Full review||Other||Yang J, D'souza R, Kharrat A, Fell DB, Snelgrove JW, Murphy KE, et al. COVID-19 pandemic and population-level pregnancy and neonatal outcomes: A living systematic review and meta-analysis. Acta Obstetricia Gynecologica Scandinavica. 2021.|
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