Guidelines that are up to date and of high quality, and that address the health question can be considered for adoption or adaptation. The AGREE II Tool should be used to assess CPG quality. Although there is no consensus on a specific threshold on the AGREE tool scores, we suggest that a high-quality CPG is one that has a score of more than 60% in the “Rigour of methodology domain". Lower thresholds for guidelines developed in the context of pandemics should be considered; however, guidance for this is lacking. No specific tool is currently available to appraise HTAs.